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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabino, Liam | 3B | Springfield Cardinals | 24 | 05/01/1996 | East Stroudsburg | USA | Right | Right | 6' 0" | 205 lbs | - |
| Sanchez, Ricardo | RP | Springfield Cardinals | 23 | 04/11/1997 | Puerto Cabello | VEN | Left | Left | 5' 11" | 215 lbs | - |
| Sawyer, Dalton | SP | Midland RockHounds | 26 | 11/22/1993 | Waconia | USA | Left | Left | 6' 5" | 210 lbs | - |
| Sborz, Josh | RP | Tulsa Drillers | 26 | 12/17/1993 | McLean | USA | Right | Right | 6' 3" | 215 lbs | - |
| Scheetz, Kit | SP | Corpus Christi Hooks | 26 | 05/18/1994 | Richmond | USA | Left | Left | 5' 10" | 185 lbs | - |
| Scheiner, Jake | 3B | Arkansas Travelers | 24 | 08/13/1995 | Santa Rosa | USA | Right | Right | 6' 1" | 200 lbs | - |
| Scholtens, Jesse | SP | Amarillo Sod Poodles | 26 | 04/06/1994 | Fairfield | USA | Right | Right | 6' 4" | 230 lbs | - |
| Sepulveda, Carlos | 2B | Tulsa Drillers | 23 | 08/27/1996 | Monclova | MEX | Left | Right | 5' 10" | 170 lbs | - |
| Shaffer, Richie | 1B | Arkansas Travelers | 29 | 03/15/1991 | Charlotte | USA | Right | Right | 6' 3" | 230 lbs | - |
| Shaver, Colton | C | Corpus Christi Hooks | 24 | 09/18/1995 | Riverton | USA | Right | Right | 6' 1" | 210 lbs | - |
| Shreve, Chasen | RP | Amarillo Sod Poodles | 30 | 07/12/1990 | Las Vegas | USA | Left | Left | 6' 4" | 195 lbs | - |
| Sierra, Anibal | SS | Corpus Christi Hooks | 26 | 02/15/1994 | Santiago de Cuba | CUB | Right | Right | 6' 1" | 190 lbs | - |
| Sierra, Yaisel | RP | Tulsa Drillers | 29 | 06/05/1991 | Holguín | CUB | Right | Right | 6' 1" | 170 lbs | $5,500,000 |
| Snow, Forrest | SP | Frisco RoughRiders | 31 | 12/30/1988 | Seattle | USA | Right | Right | 6' 7" | 250 lbs | - |
| Sotillet, Andres | SP | Northwest Arkansas Naturals | 23 | 03/02/1997 | Cumana | VEN | Right | Right | 6' 1" | 175 lbs | - |
| Speier, Gabe | CL | Northwest Arkansas Naturals | 25 | 04/12/1995 | Santa Barbara | USA | Left | Left | 6' 0" | 175 lbs | - |
| Spingola, Daniel | LF | Frisco RoughRiders | 27 | 05/05/1993 | Chapel Hill | USA | Left | Left | 6' 1" | 180 lbs | - |
| Spitzbarth, Shea | RP | Tulsa Drillers | 25 | 10/04/1994 | New York | USA | Right | Right | 6' 1" | 195 lbs | - |
| Spitznagel, Ben | CF | Midland RockHounds | 25 | 08/30/1994 | Cincinnati | USA | Left | Right | 5' 11" | 175 lbs | - |
| Sundberg, Jack | LF | Amarillo Sod Poodles | 26 | 07/21/1993 | Mansfield | USA | Left | Right | 5' 11" | 195 lbs | - |
