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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Day, Darren | RP | Atlanta Braves | 37 | 10/22/1982 | Jacksonville | USA | Right | Right | 6' 4" | 220 lbs | $2,250,000 |
| O'Hearn, Ryan | 1B | Kansas City Royals | 26 | 07/26/1993 | Frisco | USA | Left | Left | 6' 3" | 200 lbs | $563,500 |
| O'Neill, Tyler | LF | St. Louis Cardinals | 25 | 06/22/1995 | Vancouver | CAN | Right | Right | 5' 11" | 210 lbs | $564,000 |
| Oaks, Trevor | RP | San Francisco Giants | 27 | 03/26/1993 | Riverside | USA | Right | Right | 6' 3" | 225 lbs | $563,500 |
| Oberg, Scott | CL | Colorado Rockies | 30 | 03/13/1990 | Tewksbury | USA | Right | Right | 6' 2" | 200 lbs | $2,000,000 |
| Ocampo, Danny | 3B | Boston Red Sox | 16 | 04/24/2004 | Barcelona | ESP | Right | Right | 6' 1" | 175 lbs | - |
| Ochoa, Nelvis | RP | Colorado Rockies | 17 | 01/18/2003 | Valencia | VEN | Right | Right | 5' 10" | 160 lbs | - |
| Ochoa, Willis | RF | New York Yankees | 16 | 04/08/2004 | Santo Domingo | DOM | Left | Left | 6' 3" | 185 lbs | - |
| Odor, Rougned | 2B | Texas Rangers | 26 | 02/03/1994 | Maracaibo | VEN | Left | Right | 5' 11" | 195 lbs | $9,000,000 |
| Odorizzi, Jake | SP | Minnesota Twins | 30 | 03/27/1990 | Breese | USA | Right | Right | 6' 2" | 190 lbs | $17,800,000 |
| Ohtani, Shohei | SP | Los Angeles Angels | 26 | 07/05/1994 | Iwate | JPN | Left | Right | 6' 4" | 210 lbs | $700,000 |
| Okert, Steven | RP | Philadelphia Phillies | 29 | 07/09/1991 | Riverside | USA | Left | Left | 6' 2" | 200 lbs | $563,500 |
| Olivar, Ricardo | C | Minnesota Twins | 18 | 08/10/2001 | Barquisimeto | VEN | Right | Right | 5' 10" | 180 lbs | - |
| Olson, Matt | 1B | Oakland Athletics | 26 | 03/29/1994 | Atlanta | USA | Left | Right | 6' 5" | 230 lbs | $603,500 |
| Olvera, Moises | SP | Seattle Mariners | 16 | 06/20/2004 | Villa Altagracia | DOM | Left | Left | 6' 6" | 195 lbs | - |
| Oropeza, Riordan | RP | New York Yankees | 18 | 01/12/2002 | Guanare | VEN | Right | Right | 6' 3" | 180 lbs | - |
| Orozco, Hector | 3B | New York Mets | 16 | 06/03/2004 | Santo Domingo | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Osoria, Yojeiry | SP | Pittsburgh Pirates | 17 | 01/24/2003 | Puerto Plata | DOM | Left | Left | 6' 1" | 190 lbs | - |
| Osorio, Luis | RP | Arizona Diamondbacks | 17 | 01/31/2003 | Barcelona | VEN | Right | Right | 6' 3" | 175 lbs | - |
| Osuna, Roberto | CL | Houston Astros | 25 | 02/07/1995 | Juan José Ríos | MEX | Right | Right | 6' 2" | 215 lbs | $10,000,000 |
| Otero, Dan | RP | New York Yankees | 35 | 02/19/1985 | Miami | USA | Right | Right | 6' 3" | 205 lbs | $563,500 |
| Ottavino, Adam | RP | New York Yankees | 34 | 11/22/1985 | New York | USA | Switch | Right | 6' 5" | 220 lbs | $8,000,000 |
| Ozoria, Julio | LF | Toronto Blue Jays | 17 | 11/06/2002 | Unknown | USA | Right | Right | 6' 3" | 180 lbs | - |
| Ozuna, Marcell | LF | Atlanta Braves | 29 | 11/12/1990 | Santo Domingo | DOM | Right | Right | 6' 1" | 225 lbs | $18,000,000 |
